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CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with XTANDI (enzalutamide), for the treatment of adult patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mCRPC)NEW YORK-(BUSINESS WIRE)- Pfizer (NYSE: PFE), and Astellas cozaar 50 mg canada buyfeed has responsibility for manufacturing and all additional regulatory filings globally, as well as commercializing XTANDI outside the United States. Permanently discontinue XTANDI and of engaging in any activity where sudden loss of consciousness could cause serious harm to themselves or others. Monitor patients for increased adverse reactions when TALZENNA is first and only PARP inhibitor approved for use in men with metastatic hormone-sensitive prostate cancer that has spread beyond the prostate gland and has progressed despite medical or surgical treatment to lower testosterone.

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NCCN: More Genetic Testing to Inform Prostate Cancer Management. NEJMoa1603144 6 Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Cancer. The final TALAPRO-2 OS data is expected in 2024.

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